Version 5.4
Mus musculus Gene: Pcbp4
Summary
InnateDB Gene IDBG-196192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcbp4
Gene Name poly(rC) binding protein 4
Synonyms 1200003L19Rik; AlphaCP-4
Species Mus musculus
Ensembl Gene ENSMUSG00000023495
Encoded Proteins
IDBP-196194
poly(rC) binding protein 4
IDBP-787792
poly(rC) binding protein 4
IDBP-787797
poly(rC) binding protein 4
IDBP-787800
poly(rC) binding protein 4
IDBP-787804
poly(rC) binding protein 4
IDBP-787806
poly(rC) binding protein 4
IDBP-787810
poly(rC) binding protein 4
IDBP-787814
poly(rC) binding protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090097:
This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:106453291-106464012
Strand Forward strand
Band F1
Transcripts
ENSMUST00000024260 ENSMUSP00000024260
ENSMUST00000185874 ENSMUSP00000141057
ENSMUST00000185854
ENSMUST00000187975
ENSMUST00000186519
ENSMUST00000185779 ENSMUSP00000140629
ENSMUST00000185831
ENSMUST00000190430 ENSMUSP00000140485
ENSMUST00000190799
ENSMUST00000189099 ENSMUSP00000139991
ENSMUST00000185507 ENSMUSP00000140660
ENSMUST00000189882
ENSMUST00000190428 ENSMUSP00000139587
ENSMUST00000185996
ENSMUST00000188396 ENSMUSP00000139771
ENSMUST00000188448
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003723 RNA binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090097
View Gene Order
ENSBTAG00000018622
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_021567 XM_006511779 XM_006511780
OMIM
CCDS CCDS23479
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca