Version 5.4
Mus musculus Gene: Extl1
Summary
InnateDB Gene IDBG-196212.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Extl1
Gene Name exostoses (multiple)-like 1
Synonyms D430033M16Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000028838
Encoded Proteins
IDBP-196214
exostoses (multiple)-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158008:
This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:134356372-134383850
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000030643 ENSMUSP00000030643
ENSMUST00000132387
ENSMUST00000142730
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016758 transferase activity, transferring hexosyl groups
GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000158008
View Gene Order
ENSBTAG00000006349
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00534
Glycosaminoglycan biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00534
Glycosaminoglycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q9JKV7
TrEMBL Q3TSP4
UniProt Splice Variant
Entrez Gene 56219
UniGene Mm.30978 Mm.410119
RefSeq NM_019578 XM_006539058
OMIM
CCDS CCDS18770
HPRD
IMGT
MGI ID MGI:1888742
MGI Symbol Extl1
EMBL AF224461 AK161915 AL669982
GenPept AAF61913 BAE36631
RNA Seq Atlas 56219

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca