Version 5.4
Mus musculus Gene: Bnc1
Summary
InnateDB Gene IDBG-196696.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bnc1
Gene Name basonuclin 1
Synonyms AI047752; AW546376; Bnc
Species Mus musculus
Ensembl Gene ENSMUSG00000025105
Encoded Proteins
IDBP-196698
basonuclin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169594:
The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. This gene seems to have multiple alternatively spliced transcript variants, but their full-length nature is not known yet. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. Alternative splicing of this gene results in multiple transcript variants, and multiple polyadenylation sites are indicated.[provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:81966672-81992299
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000026096 ENSMUSP00000026096
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006356 regulation of transcription from RNA polymerase I promoter
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0042060 wound healing
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051276 chromosome organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169594
View Gene Order
ENSBTAG00000015462
Not yet available
Cross-References
SwissProt
TrEMBL F8VPY0
UniProt Splice Variant
Entrez Gene 12173
UniGene Mm.243802 Mm.467865
RefSeq NM_007562
OMIM
CCDS CCDS52285
HPRD
IMGT
MGI ID MGI:1097164
MGI Symbol Bnc1
EMBL AC161216
GenPept
RNA Seq Atlas 12173

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca