Version 5.4
Mus musculus Gene: Rap1gds1
Summary
InnateDB Gene IDBG-196750.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rap1gds1
Gene Name RAP1, GTP-GDP dissociation stimulator 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028149
Encoded Proteins
IDBP-196752
RAP1, GTP-GDP dissociation stimulator 1
IDBP-196754
RAP1, GTP-GDP dissociation stimulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138698:
The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:138925906-139075199
Strand Reverse strand
Band H1
Transcripts
ENSMUST00000098574 ENSMUSP00000096173
ENSMUST00000029796 ENSMUSP00000029796
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0014829 vascular smooth muscle contraction
GO:0015991 ATP hydrolysis coupled proton transport
GO:0031034 myosin filament assembly
GO:0032321 positive regulation of Rho GTPase activity
GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
GO:0051561 positive regulation of mitochondrial calcium ion concentration
Cellular Component
GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138698
View Gene Order
ENSBTAG00000007522
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
rac1_reg_pathway
Regulation of RAC1 activity
Cross-References
SwissProt
TrEMBL E9Q6Q4
UniProt Splice Variant
Entrez Gene 229877
UniGene Mm.28893 Mm.456307
RefSeq NM_145544 NM_001040690 NM_001286759 XM_006501428 XM_006501429
OMIM
CCDS CCDS51082 CCDS51083
HPRD
IMGT
MGI ID MGI:2385189
MGI Symbol Rap1gds1
EMBL AC110574 AC113307 AC119881
GenPept
RNA Seq Atlas 229877

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca