Version 5.4
| Mus musculus Gene: Gls2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-196800.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Gls2 | ||||||||
| Gene Name | glutaminase 2 (liver, mitochondrial) | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000044005 | ||||||||
| Encoded Proteins |
glutaminase 2 (liver, mitochondrial)
glutaminase 2 (liver, mitochondrial)
glutaminase 2 (liver, mitochondrial)
glutaminase 2 (liver, mitochondrial)
glutaminase 2 (liver, mitochondrial)
glutaminase 2 (liver, mitochondrial)
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135423:
The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:128194457-128210004 | ||||||||
| Strand | Forward strand | ||||||||
| Band | D3 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Metabolism pathway
Metabolism of amino acids and derivatives pathway
Neurotransmitter Release Cycle pathway
Neuronal System pathway
Amino acid synthesis and interconversion (transamination) pathway
Glutamate Neurotransmitter Release Cycle pathway
Transmission across Chemical Synapses pathway
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| KEGG |
D-Glutamine and D-glutamate metabolism pathway
Arginine and proline metabolism pathway
Alanine, aspartate and glutamate metabolism pathway
Proximal tubule bicarbonate reclamation pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Amino acid synthesis and interconversion (transamination) pathway
Glutamate Neurotransmitter Release Cycle pathway
Neuronal System pathway
Metabolism of amino acids and derivatives pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Release Cycle pathway
Metabolism pathway
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| KEGG |
Arginine and proline metabolism pathway
D-Glutamine and D-glutamate metabolism pathway
Alanine, aspartate and glutamate metabolism pathway
Proximal tubule bicarbonate reclamation pathway
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| INOH |
Glutamate Glutamine metabolism pathway
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| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.30102 | ||||||||
| RefSeq | NM_001033264 NM_001285777 NM_001285779 XM_006513572 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS24263 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||