Version 5.4
Mus musculus Gene: Erp29
Summary
InnateDB Gene IDBG-197333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Erp29
Gene Name endoplasmic reticulum protein 29
Synonyms 1200015M03Rik; 2810446M09Rik; AW209030; Erp28; Erp31; PDI-Db
Species Mus musculus
Ensembl Gene ENSMUSG00000029616
Encoded Proteins
IDBP-197335
endoplasmic reticulum protein 29
IDBP-257354
endoplasmic reticulum protein 29
IDBP-542161
endoplasmic reticulum protein 29
IDBP-537997
endoplasmic reticulum protein 29
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089248:
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:121428590-121452506
Strand Reverse strand
Band F
Transcripts
ENSMUST00000052590 ENSMUSP00000059275
ENSMUST00000111802 ENSMUSP00000107433
ENSMUST00000153758 ENSMUSP00000122522
ENSMUST00000130451 ENSMUSP00000117347
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0009306 protein secretion
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0009986 cell surface
GO:0016020 membrane
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000089248
View Gene Order
ENSBTAG00000006665
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8WJI4
UniProt Splice Variant
Entrez Gene 67397
UniGene Mm.154570 Mm.414703 Mm.443560 Mm.486441
RefSeq NM_026129
OMIM
CCDS CCDS19634
HPRD
IMGT
MGI ID MGI:1914647
MGI Symbol Erp29
EMBL AC129215
GenPept
RNA Seq Atlas 67397

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca