InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gtf2b

Summary

InnateDB Gene

IDBG-197413.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gtf2b

Gene Name

general transcription factor IIB

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000028271

Encoded Proteins

IDBP-197415

general transcription factor IIB

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137947:
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:142765226-142783603

Strand

Forward strand

Band

Transcripts

ENSMUST00000029938

ENSMUSP00000029938

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 74 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	9 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	74 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001047	core promoter binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0017025	TBP-class protein binding
GO:0046966	thyroid hormone receptor binding