Version 5.4
Mus musculus Gene: Myl2
Summary
InnateDB Gene IDBG-197887.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myl2
Gene Name myosin, light polypeptide 2, regulatory, cardiac, slow
Synonyms MLC-2; MLC-2v; Mlc2v; Mylpc
Species Mus musculus
Ensembl Gene ENSMUSG00000013936
Encoded Proteins
IDBP-197889
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-257474
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-257476
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-535994
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-539156
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-541210
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-540689
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-531936
myosin, light polypeptide 2, regulatory, cardiac, slow
IDBP-537099
myosin, light polypeptide 2, regulatory, cardiac, slow
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:122100951-122113472
Strand Forward strand
Band F
Transcripts
ENSMUST00000014080 ENSMUSP00000014080
ENSMUST00000111751 ENSMUSP00000107380
ENSMUST00000111750 ENSMUSP00000107379
ENSMUST00000139213 ENSMUSP00000114156
ENSMUST00000155612 ENSMUSP00000120105
ENSMUST00000147178 ENSMUSP00000121912
ENSMUST00000150535 ENSMUSP00000120274
ENSMUST00000153816 ENSMUSP00000119627
ENSMUST00000146733
ENSMUST00000123913
ENSMUST00000152744
ENSMUST00000126006 ENSMUSP00000123261
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003785 actin monomer binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0003007 heart morphogenesis
GO:0007507 heart development
GO:0009791 post-embryonic development
GO:0030308 negative regulation of cell growth
GO:0042694 muscle cell fate specification
GO:0048747 muscle fiber development
GO:0055003 cardiac myofibril assembly
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060047 heart contraction
GO:0060048 cardiac muscle contraction
Cellular Component
GO:0005856 cytoskeleton
GO:0015629 actin cytoskeleton
GO:0016459 myosin complex
GO:0030016 myofibril
GO:0031672 A band
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_232053
Striated Muscle Contraction pathway
REACT_262759
Muscle contraction pathway
KEGG
mmu04530
Tight junction pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu04670
Leukocyte transendothelial migration pathway
mmu04510
Focal adhesion pathway
mmu04260
Cardiac muscle contraction pathway
mmu05410
Hypertrophic cardiomyopathy (HCM) pathway
mmu05414
Dilated cardiomyopathy pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_010861 XM_006530186
OMIM
CCDS CCDS39252
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca