Version 5.4
| Mus musculus Gene: Clca5 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-198188.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Clca5 | ||||||||
| Gene Name | chloride channel calcium activated 5 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000036960 | ||||||||
| Encoded Proteins |
chloride channel calcium activated 5
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137975:
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:145070265-145099104 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | H2 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Stimuli-sensing channels pathway
Orphan transporters pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
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| KEGG |
Olfactory transduction pathway
Pancreatic secretion pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
Alpha6Beta4Integrin pathway
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| REACTOME |
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Orphan transporters pathway
Ion channel transport pathway
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| KEGG |
Olfactory transduction pathway
Pancreatic secretion pathway
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| INOH | |||||||||
| PID NCI |
p73 transcription factor network
Validated transcriptional targets of TAp63 isoforms
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| Cross-References | |||||||||
| SwissProt | Q8BG22 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 229933 | ||||||||
| UniGene | Mm.331420 | ||||||||
| RefSeq | NM_178697 XM_006501432 XM_006501433 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17890 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2139758 | ||||||||
| MGI Symbol | Clca5 | ||||||||
| EMBL | AK028704 AK035512 AK048276 AY161007 BC096379 | ||||||||
| GenPept | AAH96379 AAO18366 BAC26076 BAC29086 BAC33291 | ||||||||
| RNA Seq Atlas | 229933 | ||||||||