Version 5.4
Mus musculus Gene: Usp48
Summary
InnateDB Gene IDBG-198840.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Usp48
Gene Name ubiquitin specific peptidase 48
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000043411
Encoded Proteins
IDBP-198842
ubiquitin specific peptidase 48
IDBP-270016
ubiquitin specific peptidase 48
IDBP-270018
ubiquitin specific peptidase 48
IDBP-270020
ubiquitin specific peptidase 48
IDBP-270022
ubiquitin specific peptidase 48
IDBP-535316
ubiquitin specific peptidase 48
IDBP-541244
ubiquitin specific peptidase 48
IDBP-531566
ubiquitin specific peptidase 48
IDBP-539281
ubiquitin specific peptidase 48
IDBP-537120
ubiquitin specific peptidase 48
IDBP-531626
ubiquitin specific peptidase 48
IDBP-541719
ubiquitin specific peptidase 48
IDBP-531695
ubiquitin specific peptidase 48
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090686:
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:137593755-137658537
Strand Forward strand
Band D3
Transcripts
ENSMUST00000055131 ENSMUSP00000055016
ENSMUST00000105840 ENSMUSP00000101466
ENSMUST00000105839 ENSMUSP00000101465
ENSMUST00000105838 ENSMUSP00000101464
ENSMUST00000105837 ENSMUSP00000101463
ENSMUST00000153100 ENSMUSP00000123154
ENSMUST00000138599
ENSMUST00000154395
ENSMUST00000128065 ENSMUSP00000115533
ENSMUST00000152985
ENSMUST00000141426 ENSMUSP00000118084
ENSMUST00000131755 ENSMUSP00000114800
ENSMUST00000141628 ENSMUSP00000119691
ENSMUST00000151807 ENSMUSP00000115526
ENSMUST00000153869 ENSMUSP00000117989
ENSMUST00000157012 ENSMUSP00000118081
ENSMUST00000125151
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090686
View Gene Order
ENSBTAG00000006940
Not yet available
Cross-References
SwissProt
TrEMBL A2ALS9
UniProt Splice Variant
Entrez Gene 170707
UniGene Mm.218478 Mm.438731
RefSeq NM_130879 XM_006538598 XM_006538599 XM_006538600 XM_006538601 XM_006538602 XM_006538604 XM_006538605 XM_006538607 XM_006538608
OMIM
CCDS CCDS38924
HPRD
IMGT
MGI ID MGI:2158502
MGI Symbol Usp48
EMBL AL805954 BX000694
GenPept
RNA Seq Atlas 170707

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca