Version 5.4
Mus musculus Gene: Mcoln3
Summary
InnateDB Gene IDBG-198920.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mcoln3
Gene Name mucolipin 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036853
Encoded Proteins
IDBP-198922
mucolipin 3
IDBP-534743
mucolipin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000055732:
This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:146117459-146141806
Strand Forward strand
Band H2
Transcripts
ENSMUST00000039450 ENSMUSP00000038801
ENSMUST00000140214 ENSMUSP00000115655
ENSMUST00000146689
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006811 ion transport
GO:0007626 locomotory behavior
GO:0042491 auditory receptor cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000055732
View Gene Order
ENSBTAG00000016982
Not yet available
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_227861
TRP channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8R4F0
TrEMBL D3YZE2 Q3KP78
UniProt Splice Variant
Entrez Gene 171166
UniGene Mm.114683 Mm.470253
RefSeq NM_134160 XM_006501081 XM_006501082 XM_006501083 XM_006501084 XM_006501086 XM_006501087
OMIM
CCDS CCDS17900
HPRD
IMGT
MGI ID MGI:1890500
MGI Symbol Mcoln3
EMBL AC161212 AF475086 AK030819 AK033008 AK035029 AY083531 BC106856 CH466532
GenPept AAI06857 AAL84623 AAM08924 BAC27146 BAC28123 BAC28916 EDL11983 EDL11984
RNA Seq Atlas 171166

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca