Mus musculus Gene: Prkd3
Summary
InnateDB Gene IDBG-199324.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prkd3
Gene Name protein kinase D3
Synonyms 4930557O20Rik; 5730497N19Rik; Pkcnu; PKD3; Prkcn
Species Mus musculus
Ensembl Gene ENSMUSG00000024070
Encoded Proteins
protein kinase D3
protein kinase D3
protein kinase D3
protein kinase D3
protein kinase D3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115825:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:78949405-79020816
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000003191 ENSMUSP00000003191
ENSMUST00000119284 ENSMUSP00000113395
ENSMUST00000118768 ENSMUSP00000113232
ENSMUST00000118991 ENSMUSP00000112775
ENSMUST00000124229
ENSMUST00000146917
ENSMUST00000130070
ENSMUST00000168887 ENSMUSP00000132004
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004697 protein kinase C activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0009103 lipopolysaccharide biosynthetic process
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.252776 Mm.479651
RefSeq NM_001171004 NM_001171005 NM_029239
OMIM
CCDS CCDS37699 CCDS50184 CCDS50185
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas