InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Bicd1

Summary

InnateDB Gene

IDBG-199552.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bicd1

Gene Name

bicaudal D homolog 1 (Drosophila)

Synonyms

B830009D06Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000003452

Encoded Proteins

IDBP-140865

bicaudal D homolog 1 (Drosophila)

IDBP-199554

bicaudal D homolog 1 (Drosophila)

IDBP-257947

bicaudal D homolog 1 (Drosophila)

IDBP-624779

bicaudal D homolog 1 (Drosophila)

IDBP-624781

bicaudal D homolog 1 (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151746:
This gene is one of two human homologs of Drosophila bicaudal-D. It has been implicated in COPI-independent membrane transport from the Golgi apparatus to the endoplasmic reticulum. Two alternative splice variants have been described. Other alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:149408984-149563329

Strand

Forward strand

Band

Transcripts

ENSMUST00000086829	ENSMUSP00000084039
ENSMUST00000003544	ENSMUSP00000003544
ENSMUST00000111513	ENSMUSP00000107138
ENSMUST00000130270
ENSMUST00000140759
ENSMUST00000173408	ENSMUSP00000133727
ENSMUST00000174886
ENSMUST00000172926	ENSMUSP00000133986

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008093	cytoskeletal adaptor activity
GO:0017137	Rab GTPase binding
GO:0031871	proteinase activated receptor binding
GO:0034452	dynactin binding
GO:0045502	dynein binding

Biological Process

GO:0006810	transport
GO:0016032	viral process
GO:0033365	protein localization to organelle
GO:0034063	stress granule assembly
GO:0048260	positive regulation of receptor-mediated endocytosis
GO:0072385	minus-end-directed organelle transport along microtubule
GO:0072393	microtubule anchoring at microtubule organizing center
GO:1900275	negative regulation of phospholipase C activity
GO:1900276	regulation of proteinase activated receptor activity
GO:1900737	negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway

Cellular Component

GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0005829	cytosol
GO:0005881	cytoplasmic microtubule
GO:0016020	membrane
GO:0031410	cytoplasmic vesicle
GO:0048471	perinuclear region of cytoplasm
GO:0072517	host cell viral assembly compartment

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000151746

View Gene Order

ENSBTAG00000006734

Not yet available

Cross-References

SwissProt

TrEMBL

B2KG46

UniProt Splice Variant

Entrez Gene

12121

UniGene

Mm.177181 Mm.260763 Mm.400153 Mm.404531 Mm.406929 Mm.408307 Mm.471465 Mm.472645 Mm.483865

RefSeq

XM_006507017 XM_006536029 NM_001112796 NM_009753 XM_006507020 XM_006507023 XM_006507024 XM_006507025 XM_006536032 XM_006536035 XM_006536036 XM_006536037

OMIM

CCDS

CCDS39723 CCDS51962

HPRD

IMGT

MGI ID

MGI:1101760

MGI Symbol

Bicd1

EMBL

AC163647 AC164090

GenPept

RNA Seq Atlas

12121