Version 5.4
| Mus musculus Gene: Ptgfr | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-199872.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ptgfr | ||||||||
| Gene Name | prostaglandin F receptor | ||||||||
| Synonyms | AI957154; fp; PGF | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000028036 | ||||||||
| Encoded Proteins |
prostaglandin F receptor
prostaglandin F receptor
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122420:
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:151798918-151837630 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | H3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
GPCR downstream signaling pathway
Prostanoid ligand receptors pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
Eicosanoid ligand-binding receptors pathway
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| KEGG |
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Prostanoid ligand receptors pathway
Eicosanoid ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Signaling by GPCR pathway
Eicosanoid ligand-binding receptors pathway
Signal Transduction pathway
G alpha (q) signalling events pathway
Prostanoid ligand receptors pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Class A/1 (Rhodopsin-like receptors) pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | P43117 | ||||||||
| TrEMBL | Q60I90 Q8BNT7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 19220 | ||||||||
| UniGene | Mm.331442 | ||||||||
| RefSeq | NM_008966 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17913 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:97796 | ||||||||
| MGI Symbol | Ptgfr | ||||||||
| EMBL | AB073966 AB094411 AK080620 AK087833 AK141760 BC064794 CH466532 D17433 | ||||||||
| GenPept | AAH64794 BAA04251 BAC37962 BAC40021 BAC80245 BAC80246 BAE24824 EDL11940 EDL11941 | ||||||||
| RNA Seq Atlas | 19220 | ||||||||