Mus musculus Gene: Pla2g2d
Summary
InnateDB Gene IDBG-199977.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pla2g2d
Gene Name phospholipase A2, group IID
Synonyms mGIID; Splash
Species Mus musculus
Ensembl Gene ENSMUSG00000041202
Encoded Proteins
phospholipase A2, group IID
phospholipase A2, group IID
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117215:
This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:138775735-138782046
Strand Forward strand
Band D3
Transcripts
ENSMUST00000030528 ENSMUSP00000030528
ENSMUST00000105806 ENSMUSP00000101432
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PG pathway
Acyl chain remodelling of PS pathway
Acyl chain remodelling of PE pathway
Acyl chain remodelling of PI pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Synthesis of PA pathway
Phospholipid metabolism pathway
KEGG
Glycerophospholipid metabolism pathway
Arachidonic acid metabolism pathway
Ether lipid metabolism pathway
Linoleic acid metabolism pathway
alpha-Linolenic acid metabolism pathway
Vascular smooth muscle contraction pathway
Pancreatic secretion pathway
Fat digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PI pathway
Acyl chain remodelling of PS pathway
Synthesis of PA pathway
Acyl chain remodelling of PG pathway
Acyl chain remodelling of PE pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Metabolism pathway
KEGG
alpha-Linolenic acid metabolism pathway
Arachidonic acid metabolism pathway
Glycerophospholipid metabolism pathway
Linoleic acid metabolism pathway
Ether lipid metabolism pathway
Vascular smooth muscle contraction pathway
Fat digestion and absorption pathway
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.71913
RefSeq NM_011109 XM_006538657
OMIM
CCDS CCDS18833
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas