Mus musculus Gene: Capn9
Summary
InnateDB Gene IDBG-200211.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Capn9
Gene Name calpain 9
Synonyms 2200003B16Rik; GC36; nCL-4; nCL4
Species Mus musculus
Ensembl Gene ENSMUSG00000031981
Encoded Proteins
calpain 9
calpain 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135773:
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:124576111-124618731
Strand Forward strand
Band E2
Transcripts
ENSMUST00000093033 ENSMUSP00000090717
ENSMUST00000133086 ENSMUSP00000119938
ENSMUST00000133583
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Cross-References
SwissProt Q9D805
TrEMBL D3Z7U6
UniProt Splice Variant
Entrez Gene 73647
UniGene Mm.6209
RefSeq NM_023709
OMIM
CCDS CCDS40514
HPRD
IMGT
MGI ID MGI:1920897
MGI Symbol Capn9
EMBL AC126930 AC135015 AK008629 U89513
GenPept AAB69114 BAB25791
RNA Seq Atlas 73647