Version 5.4
Mus musculus Gene: Ehd4
Summary
InnateDB Gene IDBG-200475.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ehd4
Gene Name EH-domain containing 4
Synonyms 2210022F10Rik; AI197390; AI846352; AV006278; Past2
Species Mus musculus
Ensembl Gene ENSMUSG00000027293
Encoded Proteins
IDBP-200477
EH-domain containing 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103966:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:120089175-120154606
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000028755 ENSMUSP00000028755
ENSMUST00000150240
ENSMUST00000152366
ENSMUST00000148073
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006907 pinocytosis
GO:0030100 regulation of endocytosis
GO:0032456 endocytic recycling
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051260 protein homooligomerization
GO:0071363 cellular response to growth factor stimulus
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031901 early endosome membrane
GO:0048471 perinuclear region of cytoplasm
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103966
View Gene Order
ENSBTAG00000006792
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
mapktrkpathway
Trk receptor signaling mediated by the MAPK pathway
trkrpathway
Neurotrophic factor-mediated Trk receptor signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.132226 Mm.416494
RefSeq NM_133838
OMIM
CCDS CCDS16615
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca