Version 5.4
Mus musculus Gene: Mrps17
Summary
InnateDB Gene IDBG-201975.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrps17
Gene Name mitochondrial ribosomal protein S17
Synonyms 1810006P02Rik; Mprs17
Species Mus musculus
Ensembl Gene ENSMUSG00000034211
Encoded Proteins
IDBP-201977
mitochondrial ribosomal protein S17
IDBP-400237
mitochondrial ribosomal protein S17
IDBP-400235
mitochondrial ribosomal protein S17
IDBP-400236
mitochondrial ribosomal protein S17
IDBP-400234
mitochondrial ribosomal protein S17
IDBP-400233
mitochondrial ribosomal protein S17
IDBP-400232
mitochondrial ribosomal protein S17
IDBP-540181
mitochondrial ribosomal protein S17
IDBP-539136
mitochondrial ribosomal protein S17
IDBP-533219
mitochondrial ribosomal protein S17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000239789:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:129715497-129718875
Strand Forward strand
Band G1.3
Transcripts
ENSMUST00000042191 ENSMUSP00000040281
ENSMUST00000119576 ENSMUSP00000112779
ENSMUST00000118420 ENSMUSP00000112993
ENSMUST00000121339 ENSMUSP00000114125
ENSMUST00000119604 ENSMUSP00000114012
ENSMUST00000121813 ENSMUSP00000114059
ENSMUST00000119985 ENSMUSP00000112762
ENSMUST00000154358 ENSMUSP00000115189
ENSMUST00000136108 ENSMUSP00000122093
ENSMUST00000138812 ENSMUSP00000115097
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0008150 biological_process
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005840 ribosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000239789
View Gene Order
Pathways
NETPATH
REACTOME
REACT_268789
Mitochondrial translation pathway
REACT_224594
Organelle biogenesis and maintenance pathway
REACT_270125
Mitochondrial translation elongation pathway
REACT_271096
Mitochondrial translation initiation pathway
REACT_270158
Mitochondrial translation termination pathway
KEGG
mmu03010
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_267673
Mitochondrial translation pathway
REACT_267680
Mitochondrial translation initiation pathway
REACT_267602
Mitochondrial translation termination pathway
REACT_267677
Mitochondrial translation elongation pathway
KEGG
hsa03010
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.249809 Mm.405735
RefSeq NM_025450 XM_006504320 XM_006504321 XM_006504322 XM_006504323 XM_006504324
OMIM
CCDS CCDS19697
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca