Version 5.4
Mus musculus Gene: Zbtb17
Summary
InnateDB Gene IDBG-202154.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zbtb17
Gene Name zinc finger and BTB domain containing 17
Synonyms AA589413; Lp-1; Miz1; mZ13; Zfp100
Species Mus musculus
Ensembl Gene ENSMUSG00000006215
Encoded Proteins
IDBP-202156
zinc finger and BTB domain containing 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116809:
This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:141444654-141467930
Strand Forward strand
Band D3
Transcripts
ENSMUST00000006377 ENSMUSP00000006377
ENSMUST00000142438
ENSMUST00000142020
ENSMUST00000144899
ENSMUST00000142695
ENSMUST00000123477
ENSMUST00000130482
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001702 gastrulation with mouth forming second
GO:0006351 transcription, DNA-templated
GO:0007398 ectoderm development
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116809
View Gene Order
ENSBTAG00000018730
Not yet available
Pathways
NETPATH
REACTOME
REACT_239697
Unfolded Protein Response (UPR) pathway
REACT_247926
Metabolism of proteins pathway
REACT_231085
IRE1alpha activates chaperones pathway
REACT_106572
XBP1(S) activates chaperone genes pathway
KEGG
mmu04110
Cell cycle pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa04110
Cell cycle pathway
INOH
PID NCI
myc_represspathway
Validated targets of C-MYC transcriptional repression
myc_pathway
C-MYC pathway
smad2_3nuclearpathway
Regulation of nuclear SMAD2/3 signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.389590 Mm.412814 Mm.468720
RefSeq NM_009541
OMIM
CCDS CCDS18875
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca