Mus musculus Gene: Tyw1
Summary
InnateDB Gene IDBG-202329.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tyw1
Gene Name tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms AW125391; Rsafd1
Species Mus musculus
Ensembl Gene ENSMUSG00000056310
Encoded Proteins
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198874:
Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine (yW). The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals. Thus, this locus appears to be an evolving pseudogene, but may still be functional in some members of the population. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:130255619-130341563
Strand Forward strand
Band G1.3
Transcripts
ENSMUST00000044204 ENSMUSP00000047318
ENSMUST00000100662 ENSMUSP00000098226
ENSMUST00000040213 ENSMUSP00000037173
ENSMUST00000147619 ENSMUSP00000123693
ENSMUST00000173375
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005506 iron ion binding
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016829 lyase activity
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0008033 tRNA processing
GO:0008150 biological_process
GO:0055114 oxidation-reduction process
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.271296 Mm.401923
RefSeq NM_001015876 NM_178897 XM_006504331 XM_006504333
OMIM
CCDS CCDS19711 CCDS19712
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas