Version 5.4
Mus musculus Gene: Gtf2i
Summary
InnateDB Gene IDBG-202636.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gtf2i
Gene Name general transcription factor II I
Synonyms 6030441I21Rik; BAP-135; Diws1t; GtfII-I; Spin; TFII-I; WBSCR6
Species Mus musculus
Ensembl Gene ENSMUSG00000060261
Encoded Proteins
IDBP-202638
general transcription factor II I
IDBP-202640
general transcription factor II I
IDBP-258480
general transcription factor II I
IDBP-620507
general transcription factor II I
IDBP-620508
general transcription factor II I
IDBP-620509
general transcription factor II I
IDBP-620510
general transcription factor II I
IDBP-620511
general transcription factor II I
IDBP-620512
general transcription factor II I
IDBP-620514
general transcription factor II I
IDBP-620517
general transcription factor II I
IDBP-620520
general transcription factor II I
IDBP-620523
general transcription factor II I
IDBP-620524
general transcription factor II I
IDBP-620526
general transcription factor II I
IDBP-620527
general transcription factor II I
IDBP-620528
general transcription factor II I
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:134237834-134314760
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000059042 ENSMUSP00000049625
ENSMUST00000082057 ENSMUSP00000080714
ENSMUST00000111261 ENSMUSP00000106892
ENSMUST00000173341 ENSMUSP00000133444
ENSMUST00000172904
ENSMUST00000174354 ENSMUSP00000134440
ENSMUST00000174155 ENSMUSP00000133566
ENSMUST00000174513 ENSMUSP00000133489
ENSMUST00000174772 ENSMUSP00000133740
ENSMUST00000173485 ENSMUSP00000133526
ENSMUST00000172553
ENSMUST00000172715 ENSMUSP00000134035
ENSMUST00000173888 ENSMUSP00000133969
ENSMUST00000173509
ENSMUST00000174003
ENSMUST00000172600
ENSMUST00000174182
ENSMUST00000174133 ENSMUSP00000134111
ENSMUST00000172953
ENSMUST00000173887
ENSMUST00000174867 ENSMUSP00000133435
ENSMUST00000174188 ENSMUSP00000134636
ENSMUST00000173504 ENSMUSP00000134042
ENSMUST00000173263 ENSMUSP00000133905
ENSMUST00000174773
ENSMUST00000173651 ENSMUSP00000133375
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 62 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0051019 mitogen-activated protein kinase binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0014886 transition between slow and fast fiber
GO:0016525 negative regulation of angiogenesis
GO:0051481 negative regulation of cytosolic calcium ion concentration
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0042995 cell projection
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000009780
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03022
Basal transcription factors pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
NetPath_12
BCR pathway
REACTOME
KEGG
hsa03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.261570
RefSeq NM_001080746 NM_001080747 NM_001080748 NM_001080749 NM_010365 XM_006504382 XM_006504383 XM_006504385 XM_006504389 XM_006504391 XM_006504393
OMIM
CCDS CCDS39299 CCDS39300 CCDS39301 CCDS57386 CCDS57387
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca