InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Aldoc

Summary

InnateDB Gene

IDBG-202678.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aldoc

Gene Name

aldolase C, fructose-bisphosphate

Synonyms

AI847350; Aldo3; AU040929; Scrg2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000017390

Encoded Proteins

IDBP-202682

aldolase C, fructose-bisphosphate

IDBP-202684

aldolase C, fructose-bisphosphate

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109107:
This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:78322968-78327781

Strand

Forward strand

Band

Transcripts

ENSMUST00000102478	ENSMUSP00000099536
ENSMUST00000017534	ENSMUSP00000017534
ENSMUST00000148689
ENSMUST00000128032
ENSMUST00000124090
ENSMUST00000156039

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004332	fructose-bisphosphate aldolase activity
GO:0005515	protein binding
GO:0008092	cytoskeletal protein binding

Biological Process

GO:0001666	response to hypoxia
GO:0006096	glycolytic process
GO:0006915	apoptotic process
GO:0007568	aging
GO:0010243	response to organonitrogen compound
GO:0014070	response to organic cyclic compound
GO:0030388	fructose 1,6-bisphosphate metabolic process
GO:0030855	epithelial cell differentiation
GO:0031100	organ regeneration
GO:0051289	protein homotetramerization
GO:0051290	protein heterotetramerization