Version 5.4
| Mus musculus Gene: Sebox | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||
| InnateDB Gene | IDBG-202939.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Sebox | ||||||||||
| Gene Name | SEBOX homeobox | ||||||||||
| Synonyms | OG9; Og9x | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000001103 | ||||||||||
| Encoded Proteins |
SEBOX homeobox
SEBOX homeobox
|
||||||||||
| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109072:
Homeodomain proteins, such as SEBOX, play a key role in coordinating gene expression during development (Cinquanta et al., 2000 [PubMed 10922053]).[supplied by OMIM, Mar 2008] The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008] |
||||||||||
| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 11:78503447-78505081 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | B5 | ||||||||||
| Transcripts |
|
||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
|
||||||||||
| Gene Ontology | |||||||||||
Molecular Function |
|
||||||||||
| Biological Process |
|
||||||||||
| Cellular Component |
|
||||||||||
| Orthologs | |||||||||||
|
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Regulation of Complement cascade pathway
Integrin cell surface interactions pathway
Molecules associated with elastic fibres pathway
Elastic fibre formation pathway
Extracellular matrix organization pathway
Innate Immune System pathway
Syndecan interactions pathway
Immune System pathway
ECM proteoglycans pathway
Non-integrin membrane-ECM interactions pathway
Complement cascade pathway
|
||||||||||
| KEGG |
ECM-receptor interaction pathway
Focal adhesion pathway
|
||||||||||
| INOH | |||||||||||
| PID NCI |
Beta1 integrin cell surface interactions
Integrins in angiogenesis
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Signaling events mediated by VEGFR1 and VEGFR2
Beta3 integrin cell surface interactions
FOXA1 transcription factor network
Beta5 beta6 beta7 and beta8 integrin cell surface interactions
|
||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | E9Q4C2 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 18292 | ||||||||||
| UniGene | Mm.134360 | ||||||||||
| RefSeq | NM_008759 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS25107 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:108012 | ||||||||||
| MGI Symbol | Sebox | ||||||||||
| EMBL | AL591177 | ||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | 18292 | ||||||||||