InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Nlk

Summary

InnateDB Gene

IDBG-203133.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nlk

Gene Name

nemo like kinase

Synonyms

AI194375

Species

Mus musculus

Ensembl Gene

ENSMUSG00000017376

Encoded Proteins

IDBP-539119

nemo like kinase

IDBP-625291

nemo like kinase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087095:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:78567168-78697373

Strand

Reverse strand

Band

Transcripts

ENSMUST00000142739	ENSMUSP00000119345
ENSMUST00000165475
ENSMUST00000170394	ENSMUSP00000130555
ENSMUST00000165271

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004707	MAP kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008134	transcription factor binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0031625	ubiquitin protein ligase binding
GO:0042169	SH2 domain binding

Biological Process

GO:0000165	MAPK cascade
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006468	protein phosphorylation
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0016055	Wnt signaling pathway
GO:0018107	peptidyl-threonine phosphorylation
GO:0030178	negative regulation of Wnt signaling pathway
GO:0033136	serine phosphorylation of STAT3 protein
GO:0035556	intracellular signal transduction
GO:0046777	protein autophosphorylation