Version 5.4
| Mus musculus Gene: Nuf2 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-203463.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Nuf2 | ||||||||||
| Gene Name | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | ||||||||||
| Synonyms | 2410003C07Rik; AU044112; C85691; Cdca1; NUF2R | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000026683 | ||||||||||
| Encoded Proteins |
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143228:
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 1:169497934-169531464 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | H2.3 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Cell Cycle, Mitotic pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Mitotic Anaphase pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q99P69 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 66977 | ||||||||||
| UniGene | Mm.350612 | ||||||||||
| RefSeq | NM_023284 XM_006496958 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS15463 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:1914227 | ||||||||||
| MGI Symbol | Nuf2 | ||||||||||
| EMBL | AF326732 AK012011 AK089939 AK132467 AK162249 BC020026 | ||||||||||
| GenPept | AAH20026 AAK01427 BAB27973 BAC41008 BAE21183 BAE36815 | ||||||||||
| RNA Seq Atlas | 66977 | ||||||||||