Mus musculus Gene: Slc27a2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-204073.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Slc27a2 | ||||||||||||||||||||||
Gene Name | solute carrier family 27 (fatty acid transporter), member 2 | ||||||||||||||||||||||
Synonyms | ACSVL1; FATP2; Vlac; Vlacs; VLCS | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000027359 | ||||||||||||||||||||||
Encoded Proteins |
solute carrier family 27 (fatty acid transporter), member 2
solute carrier family 27 (fatty acid transporter), member 2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140284:
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 2:126552407-126588243 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | F1 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Metabolism pathway
Alpha-oxidation of phytanate pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of bile acids and bile salts pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Peroxisomal lipid metabolism pathway
Bile acid and bile salt metabolism pathway
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KEGG |
PPAR signaling pathway pathway
Peroxisome pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Alpha-oxidation of phytanate pathway
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Synthesis of bile acids and bile salts pathway
Metabolism of lipids and lipoproteins pathway
Peroxisomal lipid metabolism pathway
Bile acid and bile salt metabolism pathway
Metabolism pathway
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KEGG |
PPAR signaling pathway pathway
Peroxisome pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | A2ANX6 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 26458 | ||||||||||||||||||||||
UniGene | Mm.290044 Mm.412440 | ||||||||||||||||||||||
RefSeq | NM_011978 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS16683 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1347099 | ||||||||||||||||||||||
MGI Symbol | Slc27a2 | ||||||||||||||||||||||
EMBL | AL831764 AL844555 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 26458 | ||||||||||||||||||||||