Version 5.4
| Mus musculus Gene: St5 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-206177.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | St5 | ||||||||
| Gene Name | suppression of tumorigenicity 5 | ||||||||
| Synonyms | 2010004M01Rik; 2610305K15Rik | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000031024 | ||||||||
| Encoded Proteins |
suppression of tumorigenicity 5
suppression of tumorigenicity 5
suppression of tumorigenicity 5
suppression of tumorigenicity 5
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166444:
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:109523911-109617147 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | E3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | Q924W7 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 76954 | ||||||||
| UniGene | Mm.252009 Mm.397872 Mm.407522 | ||||||||
| RefSeq | NM_001001326 XM_006508320 XM_006508321 XM_006508322 XM_006508323 XM_006508324 XM_006508325 XM_006508326 NM_029811 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS21734 CCDS21735 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:108517 | ||||||||
| MGI Symbol | St5 | ||||||||
| EMBL | AJ307670 BC030391 BC032266 BC051034 | ||||||||
| GenPept | AAH30391 AAH32266 AAH51034 CAC38111 CAC38112 | ||||||||
| RNA Seq Atlas | 76954 | ||||||||