Version 5.4
Mus musculus Gene: Tas1r1
Summary
InnateDB Gene IDBG-206222.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tas1r1
Gene Name taste receptor, type 1, member 1
Synonyms Gpr70; T1r1; TR1
Species Mus musculus
Ensembl Gene ENSMUSG00000028950
Encoded Proteins
IDBP-206224
taste receptor, type 1, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173662:
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:152027914-152038568
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000030792 ENSMUSP00000030792
ENSMUST00000147982
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008527 taste receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050912 detection of chemical stimulus involved in sensory perception of taste
GO:0050917 sensory perception of umami taste
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173662
View Gene Order
ENSBTAG00000016734
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04742
Taste transduction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18319
Class C/3 (Metabotropic glutamate/pheromone receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04742
Taste transduction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q3U5H1
UniProt Splice Variant
Entrez Gene 110326
UniGene Mm.29232
RefSeq NM_031867
OMIM
CCDS CCDS18985
HPRD
IMGT
MGI ID MGI:1927505
MGI Symbol Tas1r1
EMBL AK153579 AL611927 CH466594
GenPept BAE32107 EDL14920
RNA Seq Atlas 110326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca