Version 5.4
Homo sapiens Gene: SH3BP5
Summary
InnateDB Gene IDBG-20659.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH3BP5
Gene Name SH3-domain binding protein 5 (BTK-associated)
Synonyms SAB; SH3BP-5
Species Homo sapiens
Ensembl Gene ENSG00000131370
Encoded Proteins
IDBP-20663
SH3-domain binding protein 5 (BTK-associated)
IDBP-366076
SH3-domain binding protein 5 (BTK-associated)
IDBP-292791
SH3-domain binding protein 5 (BTK-associated)
IDBP-366063
SH3-domain binding protein 5 (BTK-associated)
IDBP-366069
SH3-domain binding protein 5 (BTK-associated)
IDBP-366079
SH3-domain binding protein 5 (BTK-associated)
IDBP-366081
SH3-domain binding protein 5 (BTK-associated)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:15254853-15341368
Strand Reverse strand
Band p25.1
Transcripts
ENST00000383791 ENSP00000373301
ENST00000366391 ENSP00000394115
ENST00000408919 ENSP00000386231
ENST00000412806 ENSP00000400128
ENST00000426925 ENSP00000388553
ENST00000450625 ENSP00000389484
ENST00000417936 ENSP00000408246
ENST00000465894
ENST00000459627
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004860 protein kinase inhibitor activity
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0006469 negative regulation of protein kinase activity
GO:0007165 signal transduction
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021892
View Gene Order
ENSBTAG00000023377
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
bcr_5pathway
BCR signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.257761
RefSeq NM_001018009 NM_004844 XM_006713420
HUGO
OMIM
CCDS CCDS2625 CCDS43055
HPRD 12030
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca