Mus musculus Gene: Fscn1 | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-207523.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Fscn1 | ||||||||||||||||||||||
Gene Name | fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) | ||||||||||||||||||||||
Synonyms | AI663989; Fan1; fascin-1 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000029581 | ||||||||||||||||||||||
Encoded Proteins |
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
|
||||||||||||||||||||||
Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
InnateDB Annotation | |||||||||||||||||||||||
Summary |
Fscn1 contributes to the survival of dendritic cells against Listeria monocytogenes infection.
|
||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075618:
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011] This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin\'s lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011] |
||||||||||||||||||||||
Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 5:142960343-142973185 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | G2 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
|
||||||||||||||||||||||
Gene Ontology | |||||||||||||||||||||||
Molecular Function |
|
||||||||||||||||||||||
Biological Process |
|
||||||||||||||||||||||
Cellular Component |
|
||||||||||||||||||||||
Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | Q61553 | ||||||||||||||||||||||
TrEMBL | D3YWW3 D3YZR7 D3Z1X1 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 14086 | ||||||||||||||||||||||
UniGene | Mm.289707 | ||||||||||||||||||||||
RefSeq | NM_007984 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS19834 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1352745 | ||||||||||||||||||||||
MGI Symbol | Fscn1 | ||||||||||||||||||||||
EMBL | AC144818 AK167670 BC010338 BC037137 BC052408 L33726 U90355 | ||||||||||||||||||||||
GenPept | AAB41126 AAB58784 AAH10338 AAH37137 AAH52408 BAE39719 | ||||||||||||||||||||||
RNA Seq Atlas | 14086 | ||||||||||||||||||||||