Version 5.4
Mus musculus Gene: Crls1
Summary
InnateDB Gene IDBG-207541.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crls1
Gene Name cardiolipin synthase 1
Synonyms 0610009I22Rik; 4930557M15Rik; 5730490M08Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000027357
Encoded Proteins
IDBP-207543
cardiolipin synthase 1
IDBP-260946
cardiolipin synthase 1
IDBP-627981
cardiolipin synthase 1
IDBP-627983
cardiolipin synthase 1
IDBP-627984
cardiolipin synthase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088766:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:132846666-132866785
Strand Forward strand
Band F2
Transcripts
ENSMUST00000028835 ENSMUSP00000028835
ENSMUST00000110122 ENSMUSP00000105749
ENSMUST00000124834 ENSMUSP00000129509
ENSMUST00000124836 ENSMUSP00000132682
ENSMUST00000154160 ENSMUSP00000129137
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
Biological Process
GO:0008150 biological_process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000088766
View Gene Order
ENSBTAG00000000065
Not yet available
Pathways
NETPATH
REACTOME
REACT_199039
Acyl chain remodelling of PG pathway
REACT_199012
Synthesis of CL pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120920
Synthesis of CL pathway
REACT_121324
Acyl chain remodelling of PG pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PUH6
UniProt Splice Variant
Entrez Gene 66586
UniGene
RefSeq NM_001024385 NM_025646 XM_006500012
OMIM
CCDS CCDS16779 CCDS38247
HPRD
IMGT
MGI ID MGI:1913836
MGI Symbol Crls1
EMBL AL929562
GenPept
RNA Seq Atlas 66586

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca