InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Csrp2bp

Summary

InnateDB Gene

IDBG-208472.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Csrp2bp

Gene Name

cysteine and glycine-rich protein 2 binding protein

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027425

Encoded Proteins

IDBP-208476

cysteine and glycine-rich protein 2 binding protein

IDBP-628076

cysteine and glycine-rich protein 2 binding protein

IDBP-628077

cysteine and glycine-rich protein 2 binding protein

IDBP-628079

cysteine and glycine-rich protein 2 binding protein

IDBP-628080

cysteine and glycine-rich protein 2 binding protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149474:
CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:144368983-144407676

Strand

Forward strand

Band

Transcripts

ENSMUST00000028911	ENSMUSP00000028911
ENSMUST00000147747	ENSMUSP00000130785
ENSMUST00000156410	ENSMUSP00000127214
ENSMUST00000131836
ENSMUST00000130654
ENSMUST00000143318
ENSMUST00000137611
ENSMUST00000148500
ENSMUST00000125398	ENSMUSP00000129716
ENSMUST00000139812	ENSMUSP00000128694
ENSMUST00000171261

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	20 [view]
Protein-Protein	20 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0008080	N-acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0016573	histone acetylation
GO:0043966	histone H3 acetylation

Cellular Component

GO:0005634	nucleus
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
GO:0005737	cytoplasm

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000149474

View Gene Order

ENSBTAG00000018978

Not yet available

Pathways

NETPATH

REACTOME

REACT_218274

Chromatin organization pathway

REACT_226917

HATs acetylate histones pathway

REACT_202766

Chromatin modifying enzymes pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_172610

HATs acetylate histones pathway

REACT_172623

Chromatin organization pathway

REACT_172633

Chromatin modifying enzymes pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.227925 Mm.482653 Mm.490976

RefSeq

NM_001166640 NM_181417

OMIM

CCDS

CCDS16819

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas