Version 5.4
| Mus musculus Gene: Rin2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Gene | IDBG-208663.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Rin2 | ||||||||
| Gene Name | Ras and Rab interactor 2 | ||||||||
| Synonyms | 2010003K16Rik; 4632403N06Rik; AW821980; RASSF4 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000001768 | ||||||||
| Encoded Proteins |
Ras and Rab interactor 2
Ras and Rab interactor 2
Ras and Rab interactor 2
Ras and Rab interactor 2
Ras and Rab interactor 2
|
||||||||
| Protein Structure |
|
||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132669:
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011] |
||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 2:145784734-145887616 | ||||||||
| Strand | Forward strand | ||||||||
| Band | G1 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Orthologs | |||||||||
|
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Posttranslational regulation of adherens junction stability and dissassembly
|
||||||||
| Cross-References | |||||||||
| SwissProt | Q9D684 | ||||||||
| TrEMBL | E0CZD2 Q3TBT4 Q3TR60 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 74030 | ||||||||
| UniGene | Mm.228799 Mm.433263 | ||||||||
| RefSeq | XM_006500269 XM_006500270 XM_006500271 NM_028724 XM_006500272 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS50734 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1921280 | ||||||||
| MGI Symbol | Rin2 | ||||||||
| EMBL | AK014548 AK040763 AK150680 AK151332 AK152893 AK163047 AK171064 AL672100 BC005529 BC040390 BI660407 | ||||||||
| GenPept | AAH05529 AAH40390 BAB29425 BAC30697 BAE29760 BAE30311 BAE31576 BAE37170 BAE42223 CAM14337 | ||||||||
| RNA Seq Atlas | 74030 | ||||||||