Mus musculus Gene: Nsl1
Summary
InnateDB Gene IDBG-208689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nsl1
Gene Name NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000062510
Encoded Proteins
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117697:
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3\' UTR region of this gene on chromosome X. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:191063012-191084558
Strand Forward strand
Band H6
Transcripts
ENSMUST00000076952 ENSMUSP00000076220
ENSMUST00000078259 ENSMUSP00000077380
ENSMUST00000139340 ENSMUSP00000115289
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0000444 MIS12/MIND type complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3Z4S2
UniProt Splice Variant
Entrez Gene 381318
UniGene
RefSeq XM_006497181 NM_198654
OMIM
CCDS CCDS15614
HPRD
IMGT
MGI ID MGI:2685830
MGI Symbol Nsl1
EMBL AC138229
GenPept
RNA Seq Atlas 381318