Version 5.4
Homo sapiens Gene: SLC52A1
Summary
InnateDB Gene IDBG-20914.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC52A1
Gene Name solute carrier family 52, riboflavin transporter, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132517
Encoded Proteins
IDBP-20916
G protein-coupled receptor 172B
IDBP-363592
G protein-coupled receptor 172B
IDBP-593233
G protein-coupled receptor 172B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficiency of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:5032600-5052009
Strand Reverse strand
Band p13.2
Transcripts
ENST00000254853 ENSP00000254853
ENST00000424747 ENSP00000399979
ENST00000512825 ENSP00000443026
ENST00000573674
ENST00000575919
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001618 virus receptor activity
GO:0032217 riboflavin transporter activity
Biological Process
GO:0009615 response to virus
GO:0032218 riboflavin transport
Cellular Component
GO:0005887 integral component of plasma membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.632247
RefSeq NM_001104577 NM_017986 XM_005256709
HUGO
OMIM
CCDS CCDS11066
HPRD 07432
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca