Version 5.4
Mus musculus Gene: Pomp
Summary
InnateDB Gene IDBG-209157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pomp
Gene Name proteasome maturation protein
Synonyms 2510048O06Rik; Ump1
Species Mus musculus
Ensembl Gene ENSMUSG00000029649
Encoded Proteins
IDBP-209159
proteasome maturation protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132963:
The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.[provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:147860628-147875778
Strand Forward strand
Band G3
Transcripts
ENSMUST00000031654 ENSMUSP00000031654
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0043248 proteasome assembly
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0031090 organelle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132963
View Gene Order
ENSBTAG00000014024
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03050
Proteasome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03050
Proteasome pathway
INOH
PID NCI
Cross-References
SwissProt Q9CQT5
TrEMBL
UniProt Splice Variant
Entrez Gene 66537
UniGene
RefSeq NM_025624
OMIM
CCDS CCDS39402
HPRD
IMGT
MGI ID MGI:1913787
MGI Symbol Pomp
EMBL AK003439 AK011115 AK012455 AK013934 AK014296 AK167958 BC027016
GenPept AAH27016 BAB22791 BAB27410 BAB28250 BAB29067 BAB29252 BAE39956
RNA Seq Atlas 66537

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca