InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Acss1

Summary

InnateDB Gene

IDBG-209314.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Acss1

Gene Name

acyl-CoA synthetase short-chain family member 1

Synonyms

1110032O15Rik; Acas2; Acas2l; AceCS2; AI788978

Species

Mus musculus

Ensembl Gene

ENSMUSG00000027452

Encoded Proteins

IDBP-209316

acyl-CoA synthetase short-chain family member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154930:
This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:150618105-150668500

Strand

Reverse strand

Band

Transcripts

ENSMUST00000028944	ENSMUSP00000028944
ENSMUST00000154328
ENSMUST00000147135
ENSMUST00000141500
ENSMUST00000141785

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003987	acetate-CoA ligase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016208	AMP binding

Biological Process

GO:0006085	acetyl-CoA biosynthetic process
GO:0008152	metabolic process
GO:0019413	acetate biosynthetic process
GO:0019427	acetyl-CoA biosynthetic process from acetate
GO:0019542	propionate biosynthetic process