Mus musculus Gene: Cox4i2 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-209856.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Cox4i2 | ||||||
Gene Name | cytochrome c oxidase subunit IV isoform 2 | ||||||
Synonyms | Cox4b; CoxIV-2 | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000009876 | ||||||
Encoded Proteins |
cytochrome c oxidase subunit IV isoform 2
cytochrome c oxidase subunit IV isoform 2
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131055:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 2:152754173-152765037 | ||||||
Strand | Forward strand | ||||||
Band | H1 | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||
NETPATH | |||||||
REACTOME | |||||||
KEGG |
Oxidative phosphorylation pathway
Alzheimer's disease pathway
Parkinson's disease pathway
Cardiac muscle contraction pathway
Huntington's disease pathway
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INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME | |||||||
KEGG |
Alzheimer's disease pathway
Oxidative phosphorylation pathway
Parkinson's disease pathway
Huntington's disease pathway
Cardiac muscle contraction pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | Q91W29 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 84682 | ||||||
UniGene | Mm.196668 | ||||||
RefSeq | NM_053091 | ||||||
OMIM | |||||||
CCDS | CCDS16898 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | MGI:2135755 | ||||||
MGI Symbol | Cox4i2 | ||||||
EMBL | AF271382 BC049623 | ||||||
GenPept | AAH49623 AAK49433 | ||||||
RNA Seq Atlas | 84682 | ||||||