Version 5.4
Mus musculus Gene: Nfe2l1
Summary
InnateDB Gene IDBG-210006.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nfe2l1
Gene Name nuclear factor, erythroid derived 2,-like 1
Synonyms AA408798; AW212678; LCR-F1; Lcrf1; NRF1; TCF-11; TCF11
Species Mus musculus
Ensembl Gene ENSMUSG00000038615
Encoded Proteins
IDBP-210008
nuclear factor, erythroid derived 2,-like 1
IDBP-266201
nuclear factor, erythroid derived 2,-like 1
IDBP-266203
nuclear factor, erythroid derived 2,-like 1
IDBP-266205
nuclear factor, erythroid derived 2,-like 1
IDBP-536318
nuclear factor, erythroid derived 2,-like 1
IDBP-531893
nuclear factor, erythroid derived 2,-like 1
IDBP-622142
nuclear factor, erythroid derived 2,-like 1
IDBP-622143
nuclear factor, erythroid derived 2,-like 1
IDBP-622144
nuclear factor, erythroid derived 2,-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases from the use of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008]
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases from the use of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:96817414-96829968
Strand Reverse strand
Band D
Transcripts
ENSMUST00000081775 ENSMUSP00000080467
ENSMUST00000107659 ENSMUSP00000103286
ENSMUST00000107658 ENSMUSP00000103285
ENSMUST00000107657 ENSMUSP00000103284
ENSMUST00000126949 ENSMUSP00000120512
ENSMUST00000142065 ENSMUSP00000121423
ENSMUST00000134951
ENSMUST00000140138
ENSMUST00000135836
ENSMUST00000167149 ENSMUSP00000128527
ENSMUST00000167110 ENSMUSP00000127804
ENSMUST00000169828 ENSMUSP00000131585
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001190 RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001205 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030218 erythrocyte differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000082641
View Gene Order
ENSBTAG00000013653
Not yet available
Cross-References
SwissProt
TrEMBL A2A6D0 Q3V3M1 Q9CW60
UniProt Splice Variant
Entrez Gene 18023
UniGene Mm.465940 Mm.6743
RefSeq NM_001130451 NM_001130452 XM_006532443 NM_001130450 NM_001130453 NM_001130454 NM_008686
OMIM
CCDS CCDS48893 CCDS25304 CCDS48894
HPRD
IMGT
MGI ID MGI:99421
MGI Symbol Nfe2l1
EMBL AK004698 AK038187 AL596384
GenPept BAB23483 BAE20534
RNA Seq Atlas 18023

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca