Mus musculus Gene: Prss8
Summary
InnateDB Gene IDBG-210462.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prss8
Gene Name protease, serine, 8 (prostasin)
Synonyms 2410039E18Rik; AI313909; C79772; CAP1; fr; mCAP1
Species Mus musculus
Ensembl Gene ENSMUSG00000030800
Encoded Proteins
protease, serine, 8 (prostasin)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000052344:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:127925725-127930113
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000032988 ENSMUSP00000032988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0010765 positive regulation of sodium ion transport
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL Q99L44
UniProt Splice Variant
Entrez Gene 76560
UniGene Mm.5875
RefSeq NM_133351 XM_006508306
OMIM
CCDS CCDS40147
HPRD
IMGT
MGI ID MGI:1923810
MGI Symbol Prss8
EMBL AB038244 AC149222 AF378085 AF378086 AY335911 BC003851
GenPept AAH03851 AAL06319 AAL06320 AAQ91197 BAB82496
RNA Seq Atlas 76560