Version 5.4
Mus musculus Gene: Dynlrb1
Summary
InnateDB Gene IDBG-210536.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dynlrb1
Gene Name dynein light chain roadblock-type 1
Synonyms 2010012N15Rik; 2010320M17Rik; 9430076K19Rik; AV124457; Dncl2a; DNLC2A; km23-1
Species Mus musculus
Ensembl Gene ENSMUSG00000047459
Encoded Proteins
IDBP-261874
dynein light chain roadblock-type 1
IDBP-537834
dynein light chain roadblock-type 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125971:
This gene is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:155236533-155250277
Strand Forward strand
Band H1
Transcripts
ENSMUST00000054912
ENSMUST00000109682 ENSMUSP00000105304
ENSMUST00000150602 ENSMUSP00000114928
ENSMUST00000135831
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006810 transport
GO:0007632 visual behavior
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125971
View Gene Order
ENSBTAG00000006134
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
tgfbrpathway
TGF-beta receptor signaling
Cross-References
SwissProt P62627
TrEMBL
UniProt Splice Variant
Entrez Gene 67068
UniGene
RefSeq NM_025947 NM_001291108 XM_006500060
OMIM
CCDS CCDS38294 CCDS71166
HPRD
IMGT
MGI ID MGI:1914318
MGI Symbol Dynlrb1
EMBL AK002359 AK003435 AK008595 AK166685 AL929588 BC099423 BC125610 BC125648
GenPept AAH99423 AAI25611 AAI25649 BAB22038 BAB22788 BAB25768 BAE38944 CAM27181
RNA Seq Atlas 67068

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca