Version 5.4
Mus musculus Gene: Epb4.1l1
Summary
InnateDB Gene IDBG-210892.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Epb4.1l1
Gene Name erythrocyte protein band 4.1-like 1
Synonyms 4.1N; Epb41l1; mKIAA0338; NBL1
Species Mus musculus
Ensembl Gene ENSMUSG00000027624
Encoded Proteins
IDBP-210894
erythrocyte protein band 4.1-like 1
IDBP-210898
erythrocyte protein band 4.1-like 1
IDBP-210900
erythrocyte protein band 4.1-like 1
IDBP-210904
erythrocyte protein band 4.1-like 1
IDBP-262097
erythrocyte protein band 4.1-like 1
IDBP-262101
erythrocyte protein band 4.1-like 1
IDBP-262103
erythrocyte protein band 4.1-like 1
IDBP-539683
erythrocyte protein band 4.1-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088367:
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:156420909-156543214
Strand Forward strand
Band H1
Transcripts
ENSMUST00000103137 ENSMUSP00000099426
ENSMUST00000103136 ENSMUSP00000099425
ENSMUST00000103135 ENSMUSP00000099424
ENSMUST00000029155 ENSMUSP00000029155
ENSMUST00000109577 ENSMUSP00000105205
ENSMUST00000109574 ENSMUSP00000105202
ENSMUST00000109572 ENSMUSP00000105200
ENSMUST00000142048
ENSMUST00000125153 ENSMUSP00000121161
ENSMUST00000141109
ENSMUST00000144013
ENSMUST00000137067
ENSMUST00000129999
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
Biological Process
GO:0030866 cortical actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0019898 extrinsic component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000088367
View Gene Order
ENSBTAG00000001640
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04530
Tight junction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18307
Trafficking of AMPA receptors pathway
REACT_13685
Neuronal System pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_18347
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
KEGG
hsa04530
Tight junction pathway
INOH
PID NCI
pi3kplctrkpathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.20852 Mm.468316 Mm.489434
RefSeq NM_001003815 NM_001006664 NM_001291120 NM_001291121 NM_001291122 NM_001291123 NM_013510 XM_006498718 XM_006498719 XM_006498720 XM_006498722 XM_006498724 XM_006498726
OMIM
CCDS CCDS16966 CCDS71169 CCDS71170
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca