Version 5.4
Mus musculus Gene: Dsn1
Summary
InnateDB Gene IDBG-211062.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dsn1
Gene Name DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
Synonyms 1700022L09Rik; AW552447
Species Mus musculus
Ensembl Gene ENSMUSG00000027635
Encoded Proteins
IDBP-211064
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
IDBP-211066
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
IDBP-535020
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
IDBP-539325
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
IDBP-534721
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149636:
This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:156995265-157007154
Strand Reverse strand
Band H1
Transcripts
ENSMUST00000103130 ENSMUSP00000099419
ENSMUST00000103129 ENSMUSP00000099418
ENSMUST00000146413 ENSMUSP00000122524
ENSMUST00000141388
ENSMUST00000124671 ENSMUSP00000120354
ENSMUST00000154213 ENSMUSP00000122593
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0008150 biological_process
GO:0051301 cell division
Cellular Component
GO:0000444 MIS12/MIND type complex
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149636
View Gene Order
ENSBTAG00000013915
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_202512
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.394343
RefSeq NM_025853
OMIM
CCDS CCDS16972
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca