Version 5.4
Mus musculus Gene: Rpn2
Summary
InnateDB Gene IDBG-211228.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rpn2
Gene Name ribophorin II
Synonyms 1300012C06Rik; AV261018; Rpn-2
Species Mus musculus
Ensembl Gene ENSMUSG00000027642
Encoded Proteins
IDBP-211232
ribophorin II
IDBP-274269
ribophorin II
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118705:
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:157279017-157326319
Strand Forward strand
Band H1
Transcripts
ENSMUST00000029171 ENSMUSP00000029171
ENSMUST00000116380 ENSMUSP00000112081
ENSMUST00000142463
ENSMUST00000127252
ENSMUST00000150349
ENSMUST00000156007
ENSMUST00000126248
ENSMUST00000125311
ENSMUST00000123639
ENSMUST00000141934
ENSMUST00000149924
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016757 transferase activity, transferring glycosyl groups
GO:0043022 ribosome binding
Biological Process
GO:0006487 protein N-linked glycosylation
GO:0007568 aging
GO:0042493 response to drug
Cellular Component
GO:0000421 autophagic vacuole membrane
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0008250 oligosaccharyltransferase complex
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000118705
View Gene Order
ENSBTAG00000014648
Not yet available
Pathways
NETPATH
REACTOME
REACT_254308
Translation pathway
REACT_247926
Metabolism of proteins pathway
REACT_196445
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_233572
Gene Expression pathway
KEGG
mmu00510
N-Glycan biosynthesis pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_22161
Post-translational protein modification pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
REACT_221721
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_226022
Gene Expression pathway
REACT_209048
Translation pathway
REACT_213782
Metabolism of proteins pathway
KEGG
hsa00510
N-Glycan biosynthesis pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2ACG7
UniProt Splice Variant
Entrez Gene 20014
UniGene Mm.22130 Mm.465769
RefSeq NM_019642 XM_006499021
OMIM
CCDS CCDS16975
HPRD
IMGT
MGI ID MGI:98085
MGI Symbol Rpn2
EMBL AL669828
GenPept
RNA Seq Atlas 20014

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca