Version 5.4
Mus musculus Gene: Chd6
Summary
InnateDB Gene IDBG-211676.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chd6
Gene Name chromodomain helicase DNA binding protein 6
Synonyms 5430439G14Rik; 6330406J24Rik; CHD-6
Species Mus musculus
Ensembl Gene ENSMUSG00000057133
Encoded Proteins
IDBP-211678
chromodomain helicase DNA binding protein 6
IDBP-535631
chromodomain helicase DNA binding protein 6
IDBP-535585
chromodomain helicase DNA binding protein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124177:
Chromosomal DNA of eukaryotic cells is compacted by nuclear proteins to form chromatin, an organized nucleoprotein structure that can inhibit gene expression. Several multisubunit protein complexes exist to remodel the chromatin to allow patterns of cell type-specific gene expression. The protein encoded by this gene is thought to be a core member of one or more of these complexes. The encoded protein, which is a member of the SNF2/RAD54 helicase family, contains two chromodomains, a helicase domain, and an ATPase domain. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:160946978-161109075
Strand Reverse strand
Band H2
Transcripts
ENSMUST00000039782 ENSMUSP00000042291
ENSMUST00000143081
ENSMUST00000137152
ENSMUST00000155918
ENSMUST00000134178 ENSMUSP00000123240
ENSMUST00000149866
ENSMUST00000138078
ENSMUST00000137831
ENSMUST00000155066
ENSMUST00000130265 ENSMUSP00000117075
ENSMUST00000125179
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001221 transcription cofactor binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0008094 DNA-dependent ATPase activity
GO:0016787 hydrolase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
Biological Process
GO:0006200 ATP catabolic process
GO:0006351 transcription, DNA-templated
GO:0016568 chromatin modification
GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 DNA-directed RNA polymerase II, core complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124177
View Gene Order
ENSBTAG00000005733
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.122738 Mm.475478
RefSeq NM_173368 XM_006500181 XM_006500182 XM_006500184
OMIM
CCDS CCDS17000
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca