Version 5.4
| Mus musculus Gene: Ptdss2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-212007.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ptdss2 | ||||||||
| Gene Name | phosphatidylserine synthase 2 | ||||||||
| Synonyms | AI481134; AI988017; PSS2 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000025495 | ||||||||
| Encoded Proteins |
phosphatidylserine synthase 2
phosphatidylserine synthase 2
phosphatidylserine synthase 2
phosphatidylserine synthase 2
phosphatidylserine synthase 2
phosphatidylserine synthase 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174915:
Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).[supplied by OMIM, May 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:141122382-141157021 | ||||||||
| Strand | Forward strand | ||||||||
| Band | F5 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of PS pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
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| KEGG |
Glycerophospholipid metabolism pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of PS pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Metabolism pathway
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| KEGG |
Glycerophospholipid metabolism pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | G3UZC3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 27388 | ||||||||
| UniGene | Mm.293591 | ||||||||
| RefSeq | NM_013782 XM_006536197 XM_006536198 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22001 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1351664 | ||||||||
| MGI Symbol | Ptdss2 | ||||||||
| EMBL | AC108908 AC109272 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 27388 | ||||||||