Version 5.4
| Mus musculus Gene: Ubtf | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-212569.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Ubtf | ||||||||||||||||||||||
| Gene Name | upstream binding transcription factor, RNA polymerase I | ||||||||||||||||||||||
| Synonyms | A930005G04Rik; NOR-90; Tcfubf; UBF; UBF1 | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000020923 | ||||||||||||||||||||||
| Encoded Proteins |
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
upstream binding transcription factor, RNA polymerase I
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| Protein Structure | |||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108312:
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 11:102304560-102319742 | ||||||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||||||
| Band | D | ||||||||||||||||||||||
| Transcripts | |||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
RNA Polymerase I Transcription Termination pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Promoter Opening pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase I Transcription pathway
Epigenetic regulation of gene expression pathway
RNA Polymerase I Promoter Clearance pathway
NoRC negatively regulates rRNA expression pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
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| KEGG | |||||||||||||||||||||||
| INOH | |||||||||||||||||||||||
| PID NCI |
Regulation of retinoblastoma protein
Validated targets of C-MYC transcriptional activation
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| Cross-References | |||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||
| TrEMBL | A2AWT5 | ||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | 21429 | ||||||||||||||||||||||
| UniGene | Mm.2845 Mm.468734 | ||||||||||||||||||||||
| RefSeq | NM_001044383 NM_011551 XM_006532815 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS25495 CCDS36343 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | MGI:98512 | ||||||||||||||||||||||
| MGI Symbol | Ubtf | ||||||||||||||||||||||
| EMBL | AL954730 CH466558 | ||||||||||||||||||||||
| GenPept | EDL34113 | ||||||||||||||||||||||
| RNA Seq Atlas | 21429 | ||||||||||||||||||||||