Mus musculus Gene: Slc13a3
Summary
InnateDB Gene IDBG-212716.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc13a3
Gene Name solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000018459
Encoded Proteins
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158296:
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:165405028-165473230
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000029208 ENSMUSP00000029208
ENSMUST00000109279 ENSMUSP00000104902
ENSMUST00000145513
ENSMUST00000143136
ENSMUST00000147107
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015362 high affinity sodium:dicarboxylate symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0006835 dicarboxylic acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Sodium-coupled sulphate, di- and tri-carboxylate transporters pathway
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Sodium-coupled sulphate, di- and tri-carboxylate transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.250738
RefSeq NM_054055 XM_006498586
OMIM
CCDS CCDS17081
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas