Version 5.4
Mus musculus Gene: Bcas1
Summary
InnateDB Gene IDBG-213225.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bcas1
Gene Name breast carcinoma amplified sequence 1
Synonyms 2210416M21Rik; 9030223A09Rik; AI841227; NABC1
Species Mus musculus
Ensembl Gene ENSMUSG00000013523
Encoded Proteins
IDBP-213227
breast carcinoma amplified sequence 1
IDBP-213229
breast carcinoma amplified sequence 1
IDBP-262996
breast carcinoma amplified sequence 1
IDBP-537500
breast carcinoma amplified sequence 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064787:
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:170346991-170427845
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000068137 ENSMUSP00000069437
ENSMUST00000013667 ENSMUSP00000013667
ENSMUST00000109152 ENSMUSP00000104780
ENSMUST00000154650 ENSMUSP00000122298
ENSMUST00000156657
ENSMUST00000133673
ENSMUST00000152461
ENSMUST00000147577
ENSMUST00000145920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0042803 protein homodimerization activity
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000064787
View Gene Order
ENSBTAG00000000835
Not yet available
Cross-References
SwissProt
TrEMBL A2AVX1 Q80ZP3
UniProt Splice Variant
Entrez Gene 76960
UniGene
RefSeq NM_001164369 NM_029815 XM_006500387
OMIM
CCDS CCDS17121 CCDS50806
HPRD
IMGT
MGI ID MGI:1924210
MGI Symbol Bcas1
EMBL AL928812 AL935134 BC048647
GenPept AAH48647
RNA Seq Atlas 76960

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca