Version 5.4
Mus musculus Gene: Cd79b
Summary
InnateDB Gene IDBG-213455.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd79b
Gene Name CD79B antigen
Synonyms B29; Ig-beta; Igb; Igbeta
Species Mus musculus
Ensembl Gene ENSMUSG00000040592
Encoded Proteins
IDBP-213457
CD79B antigen
IDBP-620783
CD79B antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000007312:
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:106311341-106314762
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000044228 ENSMUSP00000048239
ENSMUST00000167143 ENSMUSP00000129029
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0050853 B cell receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019815 B cell receptor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000007312
View Gene Order
ENSBTAG00000044204
Not yet available
Pathways
NETPATH
REACTOME
REACT_188199
Signaling by the B Cell Receptor (BCR) pathway
REACT_188194
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
REACT_230745
Immune System pathway
REACT_229531
Adaptive Immune System pathway
KEGG
mmu04662
B cell receptor signaling pathway pathway
INOH
INOH website
B cell receptor signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_12
BCR pathway
REACTOME
REACT_118700
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_118773
Signaling by the B Cell Receptor (BCR) pathway
KEGG
hsa04662
B cell receptor signaling pathway pathway
INOH
INOH website
B cell receptor signaling pathway
PID NCI
bcr_5pathway
BCR signaling pathway
Cross-References
SwissProt
TrEMBL B1ARJ9
UniProt Splice Variant
Entrez Gene 15985
UniGene Mm.2987
RefSeq NM_008339
OMIM
CCDS CCDS48960
HPRD
IMGT
MGI ID MGI:96431
MGI Symbol Cd79b
EMBL AF002279 AK143573 AL604045 BC012226 CT010358 J03857
GenPept AAA37274 AAB93965 AAH12226 BAE25444 CAJ18566
RNA Seq Atlas 15985

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca